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Tirzepatide
Also indexed as LY3298176 · GIP/GLP-1 dual agonist
No independent assay has been published for this product yet. Nothing shown on this page is a measurement of the material in stock.
All products currently listed on this site are for research purposes only.
A lipidated 39-residue dual agonist of the GIP and GLP-1 receptors, and the reference compound for incretin co-agonism studies.
Size
$39.99
$70.00
Save 43%Shown with code SAVE20 · your cart shows $49.99 until you enter it at checkout
per unit · EP-TIR-005
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Delivery time depends on your service and destination. See shipping detailsAdd 2 more to reach $47.49 per unit.
| Quantity | Unit price | Saving |
|---|---|---|
| 1–2 | $49.99 | — |
| 3–5 | $47.49 | 5% |
| 6–8 | $44.99 | 10% |
| 9+ | $42.49 | 15% |
No independent assay has been published for the 5mg lot yet. Its certificate appears here when it is completed. Until then nothing published for this product is a measurement of the material in the vial.
Literature
Research context
Tirzepatide is a synthetic peptide built on an exendin-like backbone with two α-aminoisobutyric acid substitutions and a C20 fatty diacid conjugated at Lys20. The published literature examines its biased signalling at GIPR and GLP-1R, receptor internalisation kinetics, and comparative potency against selective agonists in cell-based cAMP assays.
Documented research areas
- Dual GIP/GLP-1 receptor agonism
- Biased receptor signalling and β-arrestin recruitment
- cAMP accumulation assays
- Fatty-acid conjugation and albumin binding
Specification
Chemistry
- CAS number
- 2023788-19-2
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813.45 g/mol
- Form
- Lyophilized powder
- Appears in
- 4 documented research areas
- Amino acid sequence
- YAibEGTFTSDYSIAibLDKIAQKAFVQWLIAGGPSSGAPPPS-NH2 (Lys20 γGlu-C20 diacid)
Laboratory
Storage and handling
Storage
Store lyophilized powder at -20°C, protected from light and moisture.
Handling
For laboratory use by qualified personnel only.
Research use only. This material is supplied for laboratory research by qualified personnel. It is not a drug, food, cosmetic or household product, and it is not for human or veterinary use. See our research use policy and prohibited uses.
Sources
Selected references
- Coskun et al., Mol Metab (2018) — LY3298176 dual GIP/GLP-1 receptor agonist
- Willard et al., JCI Insight (2020) — Tirzepatide receptor signalling bias
External links open in a new tab. Ethereal Peptides is not affiliated with the publishers or the authors listed.
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