
Representative render — packaging may vary
Melanotan II
Also indexed as MT-II · MT2 · Ac-Nle-cyclo[Asp-His-DPhe-Arg-Trp-Lys]-NH2
All products currently listed on this site are for research purposes only.
A cyclic lactam analogue of alpha-MSH characterised as a non-selective agonist across the melanocortin receptor family.
Size
$49.00
per unit · EP-MT2-010
Add 4 more to reach $44.00 per unit.
| Quantity | Unit price | Saving |
|---|---|---|
| 1–4 | $49.00 | — |
| 5+ | $44.00 | 10% |
| 10+ | $39.00 | 20% |
Certificate of analysis
Lot EP-MT2-2606A
99.2%
Assayed purity
Guaranteed floor 99%
- Tested
- June 4, 2026
- Laboratory
- Janoshik Analytical
- Methods
- HPLCMS
Literature
Research context
Melanotan II is a conformationally constrained heptapeptide analogue of alpha-melanocyte stimulating hormone. The published pharmacology concerns binding and functional agonism at MC1R, MC3R, MC4R and MC5R, melanogenesis in cultured melanocytes, and receptor-selectivity mapping that guided the later design of selective melanocortin ligands. Literature is preclinical and receptor-level; the compound has no approved human indication.
Documented research areas
- Melanocortin receptor agonism (MC1R/MC3R/MC4R/MC5R)
- Melanogenesis in cultured melanocytes
- Cyclic lactam peptide conformational design
- Receptor selectivity mapping
Specification
Chemistry
- CAS number
- 121062-08-6
- Molecular formula
- C50H69N15O9
- Molecular weight
- 1024.18 g/mol
- Form
- Lyophilized powder
- Purity floor
- ≥ 99%
- Appears in
- 4 documented research areas
- Amino acid sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Laboratory
Storage and handling
Storage
Store lyophilized powder at -20°C, protected from light.
Handling
For laboratory use by qualified personnel only.
Research use only. This material is supplied for laboratory research by qualified personnel. It is not a drug, food, cosmetic or household product, and it is not for human or veterinary use. See our research use policy and prohibited uses.
Sources
Selected references
- Al-Obeidi et al., J Med Chem (1989) — Cyclic alpha-MSH analogues
- Hadley & Dorr, Peptides (2006) — Melanocortin analogue pharmacology
External links open in a new tab. Ethereal Peptides is not affiliated with the publishers or the authors listed.
Nearby
Studied alongside
Skin & HairGHK-Cu
Copper Tripeptide-1
A naturally occurring copper-binding tripeptide, central to the dermal remodelling and collagen-synthesis literature.
Lyophilized powder≥99% purityLot assayed 99.6%From
$54.00
2 sizes
Research Use Only
Skin & HairGlutathione
GSH
The principal intracellular thiol antioxidant, and the reference substrate in redox-balance and detoxification assays.
Lyophilized powder≥99% purityLot assayed 99.5%From
$44.00
1 size
Research Use Only
Skin & HairPT-141
Bremelanotide
The des-amide metabolite of melanotan II, studied principally as a melanocortin-4 receptor agonist in neuroendocrine models.
Lyophilized powder≥99% purityLot assayed 99.3%From
$64.00
1 size
Research Use Only