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MOTS-c
Also indexed as Mitochondrial ORF of the 12S rRNA type-c · MOTSc
All products currently listed on this site are for research purposes only.
A sixteen-residue mitochondrial-derived peptide encoded in the 12S rRNA region, central to the retrograde-signalling literature.
Size
$69.00
per unit · EP-MTC-010
Add 2 more to reach $63.00 per unit.
| Quantity | Unit price | Saving |
|---|---|---|
| 1–2 | $69.00 | — |
| 3+ | $63.00 | 9% |
| 5+ | $56.00 | 19% |
Certificate of analysis
Lot EP-MTC-2605A
99.1%
Assayed purity
Guaranteed floor 99%
- Tested
- May 26, 2026
- Laboratory
- Janoshik Analytical
- Methods
- HPLCMS
Literature
Research context
MOTS-c is translated from a short open reading frame within mitochondrial DNA and translocates to the nucleus under metabolic stress. Published work examines AMPK activation, folate-cycle and purine-biosynthesis intermediates, and adaptive nuclear gene-expression programmes in murine skeletal muscle and cultured cells.
Documented research areas
- Mitochondrial-derived peptide biology
- AMPK pathway activation
- Folate cycle and purine biosynthesis
- Mitochondrial-to-nuclear retrograde signalling
Specification
Chemistry
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.64 g/mol
- Form
- Lyophilized powder
- Purity floor
- ≥ 99%
- Appears in
- 4 documented research areas
- Amino acid sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Laboratory
Storage and handling
Storage
Store lyophilized powder at -20°C, protected from light.
Handling
For laboratory use by qualified personnel only.
Research use only. This material is supplied for laboratory research by qualified personnel. It is not a drug, food, cosmetic or household product, and it is not for human or veterinary use. See our research use policy and prohibited uses.
Sources
Selected references
- Lee et al., Cell Metab (2015) — MOTS-c regulates metabolic homeostasis
- Reynolds et al., Nat Commun (2021) — MOTS-c and exercise adaptation in mice
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