
Representative render — packaging may vary
Humanin
Also indexed as HN · mitochondrial-derived peptide HN · MTRNR2
All products currently listed on this site are for research purposes only.
A 24-residue peptide encoded within the mitochondrial 16S rRNA gene — the first mitochondrial-derived peptide to be described.
Size
$129.00
per unit · EP-HMN-010
Add 2 more to reach $117.00 per unit.
| Quantity | Unit price | Saving |
|---|---|---|
| 1–2 | $129.00 | — |
| 3+ | $117.00 | 9% |
| 5+ | $105.00 | 19% |
Certificate of analysis
Lot EP-HMN-2605A
98.7%
Assayed purity
Guaranteed floor 98.5%
- Tested
- May 15, 2026
- Laboratory
- Janoshik Analytical
- Methods
- HPLCLC-MS
Literature
Research context
Humanin was identified in a screen of surviving neurons and is translated from a short open reading frame in mitochondrial DNA. The literature covers its binding to the formyl peptide receptor FPRL1 and the tripartite CNTFR/WSX-1/gp130 receptor complex, BAX interaction in apoptosis assays, and its relationship to the wider mitochondrial-derived peptide family including MOTS-c.
Documented research areas
- Mitochondrial-derived peptide biology
- FPRL1 and gp130 receptor engagement
- BAX interaction in apoptosis assays
- Cytoprotection in neuronal culture
Specification
Chemistry
- CAS number
- 330936-69-1
- Molecular formula
- C119H204N34O32S2
- Molecular weight
- 2687.28 g/mol
- Form
- Lyophilized powder
- Purity floor
- ≥ 98.5%
- Appears in
- 4 documented research areas
- Amino acid sequence
- MAPRGFSCLLLLTSEIDLPVKRRA
Laboratory
Storage and handling
Storage
Store lyophilized at -20°C, protected from light. Aggregation-prone in solution.
Handling
For laboratory use by qualified personnel only.
Research use only. This material is supplied for laboratory research by qualified personnel. It is not a drug, food, cosmetic or household product, and it is not for human or veterinary use. See our research use policy and prohibited uses.
Sources
Selected references
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Nearby
Studied alongside
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Mitochondrial ORF of the 12S rRNA type-c
A sixteen-residue mitochondrial-derived peptide encoded in the 12S rRNA region, central to the retrograde-signalling literature.
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Nicotinamide mononucleotide
The immediate biosynthetic precursor to NAD+ in the salvage pathway, and the most-studied NAD+ intermediate in rodent senescence work.
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