Representative render — packaging may vary
MK-677
Also indexed as Ibutamoren · Ibutamoren mesylate · MK-0677
All products currently listed on this site are for research purposes only.
A spiropiperidine GH secretagogue that acts as a non-peptide agonist at the ghrelin receptor GHS-R1a.
Size
$69.00
$79.00
per unit · EP-MKS-030
Add 2 more to reach $62.00 per unit.
| Quantity | Unit price | Saving |
|---|---|---|
| 1–2 | $69.00 | — |
| 3+ | $62.00 | 10% |
| 5+ | $56.00 | 19% |
Certificate of analysis
Lot EP-MKS-2606A
99.1%
Assayed purity
Guaranteed floor 98.5%
- Tested
- June 12, 2026
- Laboratory
- Colmaric Analyticals
- Methods
- HPLCMS
Literature
Research context
MK-677 is an orally bioavailable mimetic of the GH-releasing peptides, characterised in the literature as a GHS-R1a agonist with a long plasma half-life. Published work covers receptor binding and internalisation, pulsatile GH-axis dynamics in animal models, and its role as the reference non-peptide secretagogue in ghrelin-receptor pharmacology. Supplied as the mesylate salt.
Documented research areas
- GHS-R1a (ghrelin receptor) agonism
- Pulsatile growth-hormone axis dynamics
- IGF-1 axis signalling in animal models
- Non-peptide secretagogue pharmacology
Specification
Chemistry
- CAS number
- 159752-10-0
- Molecular formula
- C28H40N4O8S2
- Molecular weight
- 624.77 g/mol
- Form
- Solution
- Purity floor
- ≥ 98.5%
- Appears in
- 4 documented research areas
Laboratory
Storage and handling
Storage
Store at 4°C, protected from light. Do not freeze solution.
Handling
For laboratory use by qualified personnel only. Not for human or veterinary use.
Research use only. This material is supplied for laboratory research by qualified personnel. It is not a drug, food, cosmetic or household product, and it is not for human or veterinary use. See our research use policy and prohibited uses.
Sources
Selected references
- Patchett et al., Proc Natl Acad Sci USA (1995) — Design of MK-0677
- Nass et al., Ann Intern Med (2008) — Ghrelin mimetic and the GH axis
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